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You can include multimodal data like images. There’s something strange about including images when going back to Roman times or 1700 because while they had texts, they didn’t have digital images. However, this is acceptable for some purposes. You’d want to avoid leaking information that could only be known in the present. You could include things people at the time could see and experience themselves. For example, there may be no anatomically accurate painting in Roman times of a bee or an egg cracking, but you can include such images because people could see such things, even if they weren’t part of their recorded media. You could also have pictures of buildings and artifacts that we still have from the past.

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url = {https://www.anthropic.com/research/labor-market-impacts},

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In 2009, PacBio published a paper expanding the principle into a full-blown sequencing technique. Once again, each nucleotide was labeled with a different colored fluorophore detectable by the ZMW to determine which base had been incorporated. The fluorophores were attached such that they would be cleaved off during the chemical reaction incorporating the base into the growing DNA strand; they would then diffuse out of the ZMW so that the next fluorophore could be detected. Sequencing took place on a chip with many wells simultaneously — a different type of parallelization where each well detected a single DNA molecule undergoing the same basic chemical reaction.